\u570b\u7acb\u4e2d\u8208\u5927\u5b78<\/a> \u6559\u6388 Director and Professor, Graduate Institute of Genomics and Bioinformatics<\/a>, College of Life Sciences<\/a>, National Chung Hsing University<\/a>, Taiwan<\/p>\n\n\n\n \u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662<\/a> \u5206\u5b50\u8207\u57fa\u56e0\u91ab\u5b78\u7814\u7a76\u6240<\/a> \u517c\u4efb\u7814\u7a76\u54e1(2023-)<\/p>\n\n\n\n Adjunct Investigator, Institute of Molecular and Genomic Medicine<\/a>, National Health Research Institutes<\/a>, Taiwan<\/p>\n\n\n\n onion@nchu.edu.tw<\/p>\n\n\n\n Google Scholar<\/a> \u30fb Facebook<\/a> \u30fb ResearchGate<\/a><\/p>\n\n\n\n \u6211\u76f8\u4fe1\u597d\u7684\u7814\u7a76\u4f86\u81ea\u597d\u5947\u5fc3\u3001\u624e\u5be6\u8a13\u7df4\u8207\u9577\u671f\u6295\u5165\u3002 Prof. Ying-Tsong Chen<\/strong> is a faculty member at the Graduate Institute of Genomics and Bioinformatics, National Chung Hsing University.<\/p>\n\n\n\n His research centers on microbial genomics, antimicrobial resistance, pathogen evolution, and host-associated microbes. By integrating genome sequencing, bioinformatics, and molecular microbiology, his group investigates how microbes acquire resistance, virulence, and adaptive traits through genomic change and mobile genetic elements.<\/p>\n\n\n\n Recent interests include outbreak genomics of emerging pathogens, One Health microbiology, and genomic applications of endosymbionts such as Wolbachia.<\/p>\n\n\n\n Prof. Chen is committed to mentoring students through rigorous research training, interdisciplinary thinking, and problem-driven scientific inquiry.<\/p>\n\n\n\n \u9673\u6559\u6388\u73fe\u4efb\u570b\u7acb\u4e2d\u8208\u5927\u5b78\u751f\u547d\u79d1\u5b78\u9662\u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u7814\u7a76\u6240\u6559\u5e2b\uff0c\u7814\u7a76\u9818\u57df\u6db5\u84cb\u5fae\u751f\u7269\u57fa\u56e0\u9ad4\u5b78\u3001\u6297\u751f\u7d20\u6297\u85e5\u6027\u3001\u75c5\u539f\u9ad4\u6f14\u5316\uff0c\u4ee5\u53ca\u5bbf\u4e3b\u76f8\u95dc\u5fae\u751f\u7269\u3002<\/p>\n\n\n\n \u7814\u7a76\u5718\u968a\u7d50\u5408\u57fa\u56e0\u9ad4\u5b9a\u5e8f\u3001\u751f\u7269\u8cc7\u8a0a\u5206\u6790\u8207\u5206\u5b50\u5fae\u751f\u7269\u5b78\u65b9\u6cd5\uff0c\u63a2\u8a0e\u5fae\u751f\u7269\u5982\u4f55\u900f\u904e\u57fa\u56e0\u9ad4\u8b8a\u7570\u8207\u53ef\u79fb\u52d5\u907a\u50b3\u56e0\u5b50\u7372\u5f97\u6297\u85e5\u6027\u3001\u81f4\u75c5\u80fd\u529b\u53ca\u74b0\u5883\u9069\u61c9\u7279\u5fb5\u3002<\/p>\n\n\n\n \u8fd1\u5e74\u7814\u7a76\u65b9\u5411\u5305\u62ec\u65b0\u8208\u75c5\u539f\u9ad4\u7fa4\u805a\u4e8b\u4ef6\u57fa\u56e0\u9ad4\u5206\u6790\u3001One Health \u5fae\u751f\u7269\u5b78\uff0c\u4ee5\u53ca Wolbachia \u7b49\u5171\u751f\u83cc\u4e4b\u57fa\u56e0\u9ad4\u61c9\u7528\u3002<\/p>\n\n\n\n \u7814\u7a76\u5ba4\u91cd\u8996\u5b78\u751f\u7684\u7814\u7a76\u8a13\u7df4\u8207\u7368\u7acb\u601d\u8003\u80fd\u529b\uff0c\u9f13\u52f5\u8de8\u9818\u57df\u5408\u4f5c\u8207\u5be6\u52d9\u554f\u984c\u5c0e\u5411\u7684\u79d1\u5b78\u63a2\u7d22\uff0c\u6b61\u8fce\u5c0d\u7814\u7a76\u5145\u6eff\u71b1\u5ff1\u7684\u540c\u5b78\u52a0\u5165\u5718\u968a\u3002<\/p>\n<\/div><\/div>\n\n\n\n \u6211\u7684\u7814\u7a76\u5de5\u4f5c\uff0c\u5728\u65bc\u9023\u7d50\u5fae\u751f\u7269\u57fa\u56e0\u9ad4\u5b78\u8207\u5be6\u9a57\u5275\u9020\u529b\u3002\u5f88\u591a\u6642\u5019\uff0c\u6211\u6240\u505a\u7684\u662f\u5c0b\u627e\u5404\u7a2e\u9023\u7d50\u2014\u2014\u5206\u5b50\u6a5f\u5236\u8207\u751f\u7269\u610f\u7fa9\u4e4b\u9593\u3001\u6578\u64da\u8207\u7406\u89e3\u4e4b\u9593\uff0c\u4ee5\u53ca\u79d1\u5b78\u8207\u5be6\u8e10\u79d1\u5b78\u7684\u4eba\u4e4b\u9593\u3002 Graduate Institute of Genomics and Bioinformatics, COLS, NCHU Institute of Molecular and Genomic Medicine, NHRI PhD, Department of Biological Science and Technology, National Chiao Tung University 109\u5e74\u8cc7\u6df1\u512a\u826f\u6559\u5e2b(2020) Gene<\/em> (2004) https:\/\/doi.org\/10.1016\/j.gene.2004.05.008<\/a> PLOS ONE<\/em> (2012) https:\/\/doi.org\/10.1371\/journal.pone.0048737<\/a> Journal of Hospital Infection<\/em> (2021) https:\/\/doi.org\/10.1016\/j.jhin.2020.10.025<\/a> Antimicrobial Agents and Chemotherapy<\/em> (2022) https:\/\/doi.org\/10.1128\/AAC.01152-21<\/a>
\u751f\u547d\u79d1\u5b78\u9662<\/a> \u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u7814\u7a76\u6240<\/a> \u6240\u9577<\/p>\n\n\n\n
\n\n\n\n![\"ORCID](\"https:\/\/orcid.org\/sites\/default\/files\/images\/orcid_16x16.png\")
https:\/\/orcid.org\/0000-0003-1337-4127<\/a><\/div>\n\n\n\n\n
Good science begins with curiosity, grows through discipline, and succeeds through persistence.<\/p>\n<\/blockquote>\n<\/div>![\"\"](\"https:\/\/megagenome.nchu.edu.tw\/wp-content\/uploads\/2026\/07\/onion2025Jan-576x1024.jpeg\")
<\/figure><\/div>\n<\/div>\n\n\n\nAbout Professor Chen<\/h2>\n\n\n\n
\n\n\n\n![\"\"](\"https:\/\/megagenome.nchu.edu.tw\/wp-content\/uploads\/2026\/07\/onion2025May-576x1024.jpeg\")
<\/figure>\n
My work bridges microbial genomics and experimental creativity. Much of it is about finding connections\u2014between molecular mechanisms and biological meaning, between data and understanding, and between science and the people who do it. <\/p>\n<\/blockquote>\n<\/div>\n\n\n\nCareer, Education and Honors<\/h2>\n\n\n\n
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\u570b\u7acb\u4e2d\u8208\u5927\u5b78 \u751f\u547d\u79d1\u5b78\u9662 \u57fa\u56e0\u9ad4\u66a8\u751f\u7269\u8cc7\u8a0a\u7814\u7a76\u6240<\/p>\n\n\n\n\n
\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662 \u5206\u5b50\u8207\u57fa\u56e0\u91ab\u5b78\u7814\u7a76\u6240<\/p>\n\n\n\n\n
\u570b\u7acb\u4ea4\u901a\u5927\u5b78 \u751f\u7269\u79d1\u6280\u7cfb \u535a\u58eb (2000-2004)
MS, Institute of Genetics, National Yang-Ming University
\u570b\u7acb\u967d\u660e\u5927\u5b78 \u907a\u50b3\u5b78\u7814\u7a76\u6240 \u78a9\u58eb (1994-1996)
BE, Department of Bioengineering, Tatung Institute of Technology
\u5927\u540c\u5de5\u5b78\u9662 \u751f\u7269\u5de5\u7a0b\u7cfb \u5b78\u58eb (1990-1994)<\/p>\n\n\n\n
\u751f\u79d1\u9662\u63a8\u85a6\u512a\u8058\u6559\u5e2b(2018)
\u570b\u7acb\u4e2d\u8208\u5927\u5b78\u512a\u826f\u901a\u8b58\u6559\u5e2b\u734e(2015)
\u5091\u51fa\u9752\u5e74\u6559\u5e2b\u734e\u52f5(2014)<\/p>\n<\/div>![\"\"](\"https:\/\/megagenome.nchu.edu.tw\/wp-content\/uploads\/2026\/07\/onion2025Dec-576x1024.jpg\")
<\/figure><\/div>\n<\/div>\n\n\n\nFeatured publications<\/h2>\n\n\n\n
Hypervirulent Klebsiella pneumoniae plasmid pLVPK<\/h4>\n\n\n\n
One of the early complete analyses of a major virulence plasmid, revealing how mobile genetic elements contribute to hypervirulence.<\/p>\n\n\n\nNDM-1 plasmid dissemination in Klebsiella pneumoniae<\/h4>\n\n\n\n
Showed that carbapenem resistance can spread through epidemic plasmids shared across unrelated bacterial strains.<\/p>\n\n\n\nElizabethkingia anophelis outbreak from hospital water system<\/h4>\n\n\n\n
Identified a persistent hospital water reservoir responsible for a multi-year outbreak using comparative genomics.<\/p>\n\n\n\nRamAp regulator carried by IncHI2 plasmid in Salmonella enterica<\/h4>\n\n\n\n
Discovered a plasmid-borne regulator linking horizontal gene transfer with antimicrobial resistance and virulence control.<\/p>\n\n\n\nAdaptive sampling for Wolbachia genome reconstruction<\/h4>\n\n\n\n