Welcome
About the Lab
Led by Prof. Ying-Tsong Chen, the Microbial Genomics Laboratory at National Chung Hsing University studies how microorganisms evolve, spread, and influence human, animal, and environmental health. We combine genome sequencing, bioinformatics, and microbiology to investigate important questions in infectious diseases, microbial evolution, and public health.
關於研究室
微生物基因體研究室由陳盈璁教授主持，隸屬於國立中興大學基因體暨生物資訊學研究所，主要探討微生物如何演化、傳播，以及其對人類、動物與環境健康的影響。研究室結合基因體定序、生物資訊分析與微生物學方法，研究感染症、微生物演化，以及公共衛生中的重要科學問題。
Research Themes｜研究主題
Antimicrobial Resistance and Mobile Genetic Elements
抗生素抗藥性與可移動遺傳因子
Mobile genetic elements, including plasmids, integrative elements, and resistance islands, play a central role in the emergence and spread of antimicrobial resistance. In this research area, we investigate the evolution, transmission, and fitness effects of transferable resistance determinants in clinically important bacteria.
Emerging Pathogens and Outbreak Genomics
新興病原體與疫情基因體學
Using whole-genome sequencing and comparative genomics, we study the emergence, transmission, and persistence of clinically important bacterial pathogens. Research in this area supports outbreak investigation, genomic surveillance, and the tracking of newly emerging high-risk lineages.
Host–Microbe Interactions and Functional Regulation
宿主與病原菌之交互作用與基因調控
This research theme examines how bacteria regulate virulence, stress responses, and host adaptation through transcriptional networks, genome plasticity, and mobile regulators. We aim to uncover molecular mechanisms that shape pathogen behavior in host-associated environments.
Symbiotic Microbes and Vector Control Genomics
共生微生物與之基因體學應用
Our group develops adaptive sequencing methods to obtain complete genomes of endosymbiotic bacteria such as Wolbachia from complex mosquito-associated samples. Studies in this area enable genomic analyses of difficult-to-isolate symbionts and support applications in mosquito biology, disease control, and microbial ecology.
Training & Opportunities｜學習與發展機會
Students in our laboratory receive interdisciplinary training in genomics, bioinformatics, microbiology, scientific writing, and research design. We welcome students from biology, medicine, agriculture, data science, and related fields. 研究室提供基因體學、生物資訊、微生物學、科學寫作與研究設計等跨領域訓練，歡迎生命科學、醫學、農業、資料科學及相關背景學生加入。
